Effect of combination of alcohol and Betadine on the severity of inflammation in the vascular access site in hemodialysis patients

Background: Inflammation in the vascular access site results in infection, which is the second leading cause of death in hemodialysis patients. However, there is no specific protocol available for sterilization before vascular access in such patients. Aim: to determine the effect of the combination of alcohol and Betadine on the severity of inflammation in the vascular access site in hemodialysis patients Methods: In this Randomized Controlled Trial in July 2014, 68 patients undergoing hemodialysis and hospitalized in Imam Reza and Montasereye hospitals of Mashhad, were randomly assigned in two groups of control and combination of alcohol and Betadine group  for one month. In the intervention group, vascular access site was disinfected with Betadine solution and alcohol in 2:1 ratio by the researcher before starting dialysis. The common method of the ward, which was povidone iodine alone, was used to disinfect the vascular access site in control group. The vascular access site of the patients was evaluated by the Iranian Nurses Association's inflammatory criteria during 12 sessions. Data were analyzed by SPSS version 11.5 using Mann-Whitney and chi-square tests. Results: The mean of age in the intervention group was 46.8±16.6, and in control group was 54.4±1.6. Mean severity of inflammation in the intervention group (0.2±0.2) was lower than that in control group (1.1±0.4) (p